{"id":80860,"date":"2018-04-09T06:00:04","date_gmt":"2018-04-08T21:00:04","guid":{"rendered":"https:\/\/www.ishamachi.com\/?p=80860"},"modified":"2018-10-02T08:32:13","modified_gmt":"2018-10-01T23:32:13","slug":"%e5%85%8d%e7%96%ab%e7%b4%b0%e8%83%9e%e3%82%92%e6%b4%bb%e6%80%a7%e5%8c%96%e3%81%95%e3%81%9b%e3%81%a6%e3%81%8c%e3%82%93%e3%82%92%e6%b2%bb%e7%99%82%e3%81%99%e3%82%8b%e3%82%aa%e3%83%97%e3%82%b8%e3%83%bc","status":"publish","type":"post","link":"https:\/\/www.ishamachi.com\/?p=80860","title":{"rendered":"\u514d\u75ab\u7d30\u80de\u3092\u6d3b\u6027\u5316\u3055\u305b\u3066\u304c\u3093\u3092\u6cbb\u7642\u3059\u308b!?\u30aa\u30d7\u30b8\u30fc\u30dc\u3068\u306f\uff1f"},"content":{"rendered":"<h2>\u30aa\u30d7\u30b8\u30fc\u30dc\u3068\u306f<\/h2>\n<p><strong>\u30aa\u30d7\u30b8\u30fc\u30dc\u306f\u3001\u30cb\u30dc\u30eb\u30de\u30d6\u3068\u3044\u3046\u85ac\u306e\u5546\u54c1\u540d<\/strong>\u306b\u3042\u305f\u308a\u3001\u6297\u4f53\u3068\u3044\u3046\u305f\u3093\u3071\u304f\u8cea\u3067\u3067\u304d\u3066\u3044\u307e\u3059\u3002<br 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\/>\n\u5316\u5b66\u7269\u8cea\u306b\u3088\u3063\u3066\u304c\u3093\u7d30\u80de\u306e\u7d30\u80de\u5206\u88c2\u3092\u59a8\u3052\u305f\u308a\u3001\u6b63\u5e38\u7d30\u80de\u306b\u306f\u306a\u3044\u304c\u3001\u304c\u3093\u7d30\u80de\u3060\u3051\u304c\u6301\u3063\u3066\u3044\u308b\u7269\u8cea\u3092\u963b\u5bb3\u3057\u305f\u308a\u3059\u308b\u65b9\u6cd5\u306a\u3069\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u4e00\u65b9\u3001<strong>\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u5264\u306f\u3001\u304c\u3093\u7d30\u80de\u305d\u306e\u3082\u306e\u3092\u653b\u6483\u3059\u308b\u306e\u3067\u306f\u306a\u304f\u3001\u672c\u6765\u306e\u514d\u75ab\u6a5f\u80fd\u3092\u53d6\u308a\u623b\u3057\u3001\u304c\u3093\u7d30\u80de\u3078\u306e\u653b\u6483\u3092\u4fc3\u9032\u3059\u308b\u85ac<\/strong>\u3067\u3059\u3002<br \/>\n\u3053\u306e\u3088\u3046\u306b\u514d\u75ab\u3092\u6d3b\u6027\u5316\u3055\u305b\u3066\u304c\u3093\u7d30\u80de\u3092\u653b\u6483\u3059\u308b\u6cbb\u7642\u65b9\u6cd5\u306f\u3001<strong>\u304c\u3093\u514d\u75ab\u7642\u6cd5<\/strong>\u3068\u547c\u3070\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<h2>\u30aa\u30d7\u30b8\u30fc\u30dc\u306e\u8a73\u3057\u3044\u4f5c\u7528\u30e1\u30ab\u30cb\u30ba\u30e0<\/h2>\n<p>\u30aa\u30d7\u30b8\u30fc\u30dc\u306f\u3044\u3063\u305f\u3044\u3069\u306e\u3088\u3046\u306b\u3001\u514d\u75ab\u7d30\u80de\u306e\u50cd\u304d\u3092\u5f37\u3081\u3066\u3044\u308b\u306e\u3067\u3057\u3087\u3046\u304b\u3002\u3053\u3053\u3067\u306f\u5c02\u9580\u7528\u8a9e\u304c\u591a\u3081\u306b\u51fa\u3066\u304d\u3066\u3057\u307e\u3044\u307e\u3059\u304c\u3001\u305c\u3072\u30b8\u30c3\u30af\u30ea\u3068\u8aad\u3093\u3067\u307f\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<h3>\u300c\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u300d\u3068\u306f<\/h3>\n<div style=\"max-width: 400px; margin: 1rem; text-align: center;\"><a href=\"https:\/\/www.ishamachi.com\/wp-content\/uploads\/2018\/03\/180409-cancer-cell-1.jpg\"><img decoding=\"async\" src=\"https:\/\/www.ishamachi.com\/wp-content\/uploads\/2018\/03\/180409-cancer-cell-1.jpg\" alt=\"\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u3068\u306f\" \/><\/a><\/div>\n<p>\u304c\u3093\u7d30\u80de\u306b\u306f\u3001<strong>\u4e3b\u8981\u7d44\u7e54\u9069\u5408\u907a\u4f1d\u5b50\u8907\u5408\u4f53<\/strong>\uff08MHC\u3001HLA\uff1a\u4ee5\u4e0b\u3001<strong>MHC<\/strong>\u3068\u8868\u8a18\u3057\u307e\u3059\uff09\u3068\u547c\u3070\u308c\u308b\u7269\u8cea\u3068\u3001<strong>\u304c\u3093\u7d30\u80de\u7279\u6709\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u304f\u3063\u3064\u3044\u305f\u90e8\u5206<\/strong>\u304c\u3042\u308a\u307e\u3059\u3002<br \/>\n\u305d\u3057\u3066\u3001\u514d\u75ab\u7d30\u80de\u3067\u3042\u308bT\u7d30\u80de\u306e\u8868\u9762\u306b\u306f\u3001\u304c\u3093\u7d30\u80de\u306e\u5b58\u5728\u3092\u8a8d\u8b58\u3059\u308b\u305f\u3081\u306b\u3001<strong>T<\/strong><strong>\u7d30\u80de\u53d7\u5bb9\u4f53<\/strong>\uff08<strong>TCR<\/strong><strong>\uff1a<\/strong>\u304c\u3093\u7d30\u80de\u4e0a\u306eMHC\u3068\u304c\u3093\u7d30\u80de\u7279\u6709\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u304f\u3063\u3064\u3044\u305f\u90e8\u5206\u3068\u7d50\u5408\u3059\u308b\uff09\u3068\u3044\u3046\u90e8\u5206\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u3055\u3089\u306bT\u7d30\u80de\u306e\u8868\u9762\u306b\u306f\u3001<strong>PD-1<\/strong>\u3068\u3044\u3046T\u7d30\u80de\u306e\u50cd\u304d\u3092\u6291\u5236\u3059\u308b\u90e8\u5206\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u304c\u3093\u7d30\u80de\u306b\u306f<strong>PD-L1<\/strong>\u3068\u3044\u3046PD-1\u3068\u304f\u3063\u3064\u304f\u90e8\u5206\u304c\u3042\u308a\u307e\u3059\u3002<br \/>\n<strong>PD-1<\/strong><strong>\u3068PD-L1\u304c\u304f\u3063\u3064\u304f\u3068\u3001\u5148\u307b\u3069\u306e\u8aac\u660e\u306b\u767b\u5834\u3057\u305fT\u7d30\u80de\u304c\u304c\u3093\u7d30\u80de\u3092\u8a8d\u8b58\u3059\u308b\u30b7\u30b9\u30c6\u30e0\u306b\u30d6\u30ec\u30fc\u30ad\u304c\u304b\u304b\u308a\u3001T\u7d30\u80de\u306e\u50cd\u304d\u304c\u6291\u3048\u3089\u308c\u307e\u3059\u3002<\/strong><br \/>\n\u307e\u3055\u306b\u3053\u3053\u304c\u300c\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u300d\u3068\u3044\u3046\u4ed5\u7d44\u307f\u306a\u306e\u3067\u3059\u3002<\/p>\n<h2>\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u300c\u963b\u5bb3\u300d\u5264\u3068\u306f\uff1f<\/h2>\n<div style=\"max-width: 400px; margin: 1rem; text-align: center;\"><img decoding=\"async\" src=\"https:\/\/www.ishamachi.com\/wp-content\/uploads\/2018\/10\/180409-cancer-cell-2.jpg\" alt=\"\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u5264\uff08\u30aa\u30d7\u30b8\u30fc\u30dc\uff09\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\" \/><\/div>\n<p>\u3057\u304b\u3057\u3001<strong>\u304c\u3093\u7d30\u80de\u306f\u3053\u306e\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u3092\u60aa\u7528\u3057\u3066\u3001\u81ea\u8eab\u3092\u30ab\u30e2\u30d5\u30e9\u30fc\u30b8\u30e5\u3057\u3001<\/strong><strong>T<\/strong><strong>\u7d30\u80de\u306e\u653b\u6483\u304b\u3089\u9003\u308c\u3088\u3046\u3068\u3057\u307e\u3059\u3002<\/strong>\u304c\u3093\u7d30\u80de\u306fPD-L1\u3092\u8eab\u306b\u307e\u3068\u3044\u3001<strong>T<\/strong><strong>\u7d30\u80de\u306ePD-1<\/strong><strong>\u3068\u7d50\u5408\u3059\u308b\u3053\u3068\u3067\u3001T<\/strong><strong>\u7d30\u80de\u306e\u76e3\u8996\u306e\u76ee\u3092\u3042\u3056\u3080\u304d\u3001\u514d\u75ab\u7d30\u80de\u306e\u653b\u6483\u304b\u3089\u9003\u308c\u3066\u3044\u308b\u306e\u3067\u3059\u3002<br \/>\n<\/strong>\u304c\u3093\u7d30\u80de\u304c\u30ab\u30e2\u30d5\u30e9\u30fc\u30b8\u30e5\u3057\u3066\u3057\u307e\u3046\u3068\u3001<strong>T<\/strong><strong>\u7d30\u80de\u306f\u304c\u3093\u7d30\u80de\u3092\u767a\u898b\u3067\u304d\u305a\u3001\u653b\u6483\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u305b\u3093\u3002<\/strong><\/p>\n<p>\u3053\u306e\u70b9\u3001\u30aa\u30d7\u30b8\u30fc\u30dc\u306f<strong>\u30d2\u30c8\u578b\u6297\u30d2\u30c8<\/strong><strong>PD-1<\/strong><strong>\u30e2\u30ce\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f53\u3068\u3044\u3046\u30bf\u30f3\u30d1\u30af\u8cea<\/strong>\u3067\u3059\u3002<br \/>\nPD-1\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u3067\u3001<strong>T<\/strong><strong>\u7d30\u80de\u306ePD-1<\/strong><strong>\u3068\u304c\u3093\u7d30\u80de\u306ePD-L1<\/strong><strong>\u304c\u304f\u3063\u3064\u304b\u306a\u3044\u3088\u3046\u306b\u3057\u3001T<\/strong><strong>\u7d30\u80de\u306b\u3088\u308b\u304c\u3093\u7d30\u80de\u3078\u306e\u653b\u6483\u3092\u4fc3\u3057\u3066\u3044\u307e\u3059\u3002<\/strong><\/p>\n<p>\u30aa\u30d7\u30b8\u30fc\u30dc\u306a\u3069\u306e\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u5264\u3068\u306f\u3001<strong>\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u306e\u60aa\u7528\u306b\u3088\u308b\u30ab\u30e2\u30d5\u30e9\u30fc\u30b8\u30e5\u3092\u89e3\u304d\u3001\u304c\u3093\u7d30\u80de\u306b\u5bfe\u3059\u308b<\/strong><strong>T\u7d30\u80de\uff08\u514d\u75ab\u7d30\u80de\u306e\u3046\u3061\u306e\u4e00\u3064\uff09\u306e\u6d3b\u6027\u3092\u53d6\u308a\u623b\u3059\u3053\u3068\u304c\u3067\u304d\u308b\u85ac<\/strong>\u3067\u3059\u3002<\/p>\n<h2>\u9069\u5fdc\u75c7\u4f8b\u306b\u3064\u3044\u3066<\/h2>\n<p>\u30aa\u30d7\u30b8\u30fc\u30dc\u306e\u9069\u5fdc\u75c7\u4f8b\u306b\u306f\u3001\u6b21\u306e\u3088\u3046\u306a\u3082\u306e\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<ul>\n<li>\u6839\u6cbb\u5207\u9664\u4e0d\u80fd\u306a<a href=\"\/?p=30847\"><strong>\u60aa\u6027\u9ed2\u8272\u816b<\/strong><\/a><\/li>\n<li>\u5207\u9664\u4e0d\u80fd\u306a\u9032\u884c\u30fb\u518d\u767a\u306e<strong>\u975e\u5c0f\u7d30\u80de\u80ba\u304c\u3093<\/strong><\/li>\n<li>\u6839\u6cbb\u5207\u9664\u4e0d\u80fd\u307e\u305f\u306f\u8ee2\u79fb\u6027\u306e<a href=\"\/?p=27300\"><strong>\u814e\u7d30\u80de\u304c\u3093<\/strong><\/a><\/li>\n<li>\u518d\u767a\u307e\u305f\u306f\u96e3\u6cbb\u6027\u306e<strong>\u53e4\u5178\u7684<a href=\"\/?p=6501\">\u30db\u30b8\u30ad\u30f3\u30ea\u30f3\u30d1\u816b<\/a><\/strong><\/li>\n<li>\u518d\u767a\u307e\u305f\u306f\u9060\u9694\u8ee2\u79fb\u3092\u6709\u3059\u308b<strong>\u982d\u981a\u90e8\u304c\u3093<\/strong>\uff08<a href=\"\/?p=22518\">\u54bd\u982d\u304c\u3093<\/a>\u3001<a href=\"\/?p=23212\">\u53e3\u8154\u304c\u3093<\/a>\u3001<a href=\"\/?p=20388\">\u7532\u72b6\u817a\u304c\u3093<\/a>\u306a\u3069\uff09<\/li>\n<li>\u304c\u3093\u5316\u5b66\u7642\u6cd5\u5f8c\u306b\u5897\u60aa\u3057\u305f\u6cbb\u7652\u5207\u9664\u4e0d\u80fd\u306a\u9032\u884c\u30fb\u518d\u767a\u306e<a href=\"\/?p=5460\"><strong>\u80c3\u304c\u3093<\/strong><\/a><\/li>\n<\/ul>\n<p><strong>\u624b\u8853\u306b\u3088\u308b\u6cbb\u7642\u304c\u96e3\u3057\u3044\u3068\u5224\u65ad\u3055\u308c\u305f\u5834\u5408<\/strong>\u306b\u3001\u30aa\u30d7\u30b8\u30fc\u30dc\u306b\u3088\u308b\u6cbb\u7642\u304c\u9078\u629e\u3055\u308c\u307e\u3059\u3002<\/p>\n<p>\u30aa\u30d7\u30b8\u30fc\u30dc\u306b\u542b\u307e\u308c\u308b\u6210\u5206\u306b\u5bfe\u3057\u3066\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u3092\u8d77\u3053\u3057\u305f\u3053\u3068\u306e\u3042\u308b\u65b9\u306f\u3001\u30aa\u30d7\u30b8\u30fc\u30dc\u306e\u6cbb\u7642\u3092\u53d7\u3051\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u305b\u3093\u3002<br \/>\n\u307e\u305f\u3001\u904e\u53bb\u306b\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u3084\u9593\u8cea\u6027\u80ba\u75be\u60a3\u306b\u304b\u304b\u3063\u305f\u3053\u3068\u306e\u3042\u308b\u65b9\u3082\u30aa\u30d7\u30b8\u30fc\u30dc\u306b\u3088\u308b\u6cbb\u7642\u3092\u53d7\u3051\u3089\u308c\u306a\u3044\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<h2>\u30aa\u30d7\u30b8\u30fc\u30dc\u306b\u3088\u308b\u526f\u4f5c\u7528<\/h2>\n<p>\u30aa\u30d7\u30b8\u30fc\u30dc\u306b\u3088\u308b\u526f\u4f5c\u7528\u306e\u3046\u3061\u3001\u7279\u306b\u6ce8\u610f\u304c\u5fc5\u8981\u306a\u3082\u306e\u306b\u306f\u6b21\u306e\u3088\u3046\u306a\u3082\u306e\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<ul>\n<li><a href=\"\/?p=22305\">\u9593\u8cea\u6027\u80ba\u75be\u60a3<\/a><\/li>\n<li><a href=\"\/?p=30738\">\u91cd\u75c7\u7b4b\u7121\u529b\u75c7<\/a>\u3001<a href=\"\/?p=16565\">\u5fc3\u7b4b\u708e<\/a>\u3001\u7b4b\u708e\u3001\u6a2a\u7d0b\u7b4b\u878d\u89e3\u75c7<\/li>\n<li>\u5927\u8178\u708e\u3001\u4e0b\u75e2<\/li>\n<li><a href=\"\/?p=7749\">1\u578b\u7cd6\u5c3f\u75c5<\/a><\/li>\n<li>\u514d\u75ab\u6027\u8840\u5c0f\u677f\u6e1b\u5c11\u6027\u7d2b\u6591\u75c5<\/li>\n<li>\u809d\u6a5f\u80fd\u969c\u5bb3<\/li>\n<li>\u7532\u72b6\u817a\u6a5f\u80fd\u969c\u5bb3<\/li>\n<li>\u795e\u7d4c\u969c\u5bb3<\/li>\n<li>\u814e\u969c\u5bb3<\/li>\n<li>\u526f\u814e\u969c\u5bb3<\/li>\n<li>\u8133\u708e<\/li>\n<li>\u76ae\u819a\u969c\u5bb3<\/li>\n<li><a href=\"\/?p=17571\">\u9759\u8108\u8840\u6813\u585e\u6813\u75c7<\/a><\/li>\n<\/ul>\n<p>\u305d\u306e\u4ed6\u3001\u767a\u71b1\u3001\u60aa\u5bd2\u3001\u767a\u75b9\u3001\u9ad8\u8840\u5727\u3001\u4f4e\u8840\u5727\u3001\u547c\u5438\u56f0\u96e3\u306a\u3069\u3092\u542b\u3080<strong>Infusion reaction<\/strong>\u3068\u3044\u3046\u53cd\u5fdc\u304c\u73fe\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<h2>\u30aa\u30d7\u30b8\u30fc\u30dc\u306e\u85ac\u4fa1\u304c\u554f\u984c\u3068\u306a\u3063\u305f\u30ef\u30b1<\/h2>\n<p>\u305d\u306e\u7406\u7531\u306f<strong>\u85ac\u4fa1<\/strong>\uff08\u56fd\u304c\u6c7a\u3081\u3066\u3044\u308b\u533b\u7642\u7528\u533b\u85ac\u54c1\u306e\u4fa1\u683c\uff09<strong>\u306e\u6c7a\u3081\u65b9<\/strong>\u306b\u5927\u304d\u306a\u30dd\u30a4\u30f3\u30c8\u304c\u3042\u308a\u307e\u3059\u3002<br \/>\n\u65b0\u85ac\u306e\u85ac\u4fa1\u3092\u6c7a\u3081\u308b\u969b\u306b\u91cd\u8981\u306b\u306a\u308b\u306e\u304c\u3001\u540c<strong>\u3058\u3088\u3046\u306a\u52b9\u679c\u3092\u6301\u3064\u985e\u4f3c\u85ac\u304c\u3059\u3067\u306b\u8ca9\u58f2\u3055\u308c\u3066\u3044\u308b\u304b\u3069\u3046\u304b<\/strong>\u3067\u3059\u3002<\/p>\n<h3>\u985e\u4f3c\u85ac\u304c\u3042\u308b\u5834\u5408<\/h3>\n<p>\u985e\u4f3c\u85ac\u304c\u3042\u308b\u5834\u5408\u3001\u305d\u306e\u65b0\u85ac\u306e\u85ac\u4fa1\u306f<strong>\u985e\u4f3c\u85ac\u3068\u540c\u3058<\/strong>\u306b\u3057\u307e\u3059\u3002<\/p>\n<h3>\u985e\u4f3c\u85ac\u304c\u306a\u3044\u5834\u5408<\/h3>\n<p>\u985e\u4f3c\u85ac\u304c\u306a\u3044\u3068\u3044\u3046\u3053\u3068\u306f\u3001\u305d\u306e\u65b0\u85ac\u306f<strong>\u3053\u308c\u307e\u3067\u306b\u306a\u3044\u5168\u304f\u65b0\u3057\u3044\u85ac<\/strong>\u3068\u3044\u3046\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002\u30aa\u30d7\u30b8\u30fc\u30dc\u306f\u3053\u3061\u3089\u306e\u5834\u5408\u306b\u5f53\u3066\u306f\u307e\u308a\u307e\u3059\u3002<br \/>\n\u3053\u306e\u5834\u5408\u306e\u85ac\u4fa1\u306f\u3001<strong>\u7814\u7a76\u958b\u767a\u8cbb\u3084\u88fd\u9020\u8cbb\u3001\u65b0\u898f\u6027\u3084\u6709\u52b9\u6027\u3092\u52a0\u5473\u3057\u305f\u55b6\u696d\u5229\u76ca<\/strong>\u306a\u3069\u3092\u8003\u616e\u3057\u3066\u6c7a\u5b9a\u3057\u307e\u3059\u3002\u65b0\u85ac\u3092\u5229\u7528\u3059\u308b\u60a3\u8005\u3055\u3093\u304c\u591a\u3051\u308c\u3070\u591a\u3044\u307b\u3069\u5b89\u304f\u306a\u308a\u3001\u53cd\u5bfe\u306b\u5c11\u306a\u3051\u308c\u3070\u9ad8\u304f\u306a\u308a\u307e\u3059\u3002\u65b0\u85ac\u306e\u958b\u767a\u304c\u96e3\u3057\u304f\u306a\u3063\u3066\u3044\u308b\u305f\u3081\u3001\u8fd1\u5e74\u3001<strong>\u7814\u7a76\u958b\u767a\u8cbb\u306f\u4e0a\u6607\u50be\u5411<\/strong>\u306b\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u30aa\u30d7\u30b8\u30fc\u30dc\u306f<strong>\u88fd\u9020\u8cbb\u306e\u9ad8\u3044\u6297\u4f53\u3092\u5229\u7528<\/strong>\u3057\u3066\u3044\u308b\u3046\u3048\u3001<strong>\u6700\u521d\u306b\u4fdd\u967a\u9069\u7528\u3055\u308c\u305f\u306e\u304c\u60a3\u8005\u6570\u306e\u5c11\u306a\u3044\u60aa\u6027\u9ed2\u8272\u816b\u3067\u3042\u3063\u305f<\/strong>\u305f\u3081\u3001\u9ad8\u984d\u306a\u85ac\u4fa1\u3068\u306a\u308a\u3001\u8a71\u984c\u3068\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n<p>\u30aa\u30d7\u30b8\u30fc\u30dc\u306e\u85ac\u4fa1\u306f\u3001\u60a3\u8005\u6570\u306e\u591a\u3044\u975e\u5c0f\u7d30\u80de\u6027\u80ba\u304c\u3093\u3078\u306e\u9069\u5fdc\u62e1\u5927\u3092\u6a5f\u306b\u30012017\u5e742\u6708\u3001\u5f53\u521d\u306e\u85ac\u4fa1\u306e\u534a\u984d\u307e\u3067\u5f15\u304d\u4e0b\u3052\u3089\u308c\u307e\u3057\u305f\u3002<br \/>\n\u3055\u3089\u306b\u30aa\u30d7\u30b8\u30fc\u30dc\u306e\u58f2\u308a\u4e0a\u3052\u304c\u4e88\u60f3\u3092\u8d85\u3048\u305f\u3053\u3068\u304b\u3089\u30012018\u5e744\u6708\u85ac\u4fa1\u6539\u5b9a\u306e\u969b\u3001\u30aa\u30d7\u30b8\u30fc\u30dc\u306e\u73fe\u5728\u306e\u85ac\u4fa1\u304b\u3089\u3055\u3089\u306b12\uff05\u5f15\u304d\u4e0b\u3052\u3089\u308c\u308b\u3053\u3068\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n<h2>\u304c\u3093\u514d\u75ab\u7642\u6cd5\u306b\u95a2\u3059\u308b\u6ce8\u610f\u70b9<\/h2>\n<p>\u514d\u75ab\u7642\u6cd5\u306f\u3001<strong>\u514d\u75ab\u6a5f\u80fd\u3092\u56de\u5fa9\u3055\u305b\u3066\u304c\u3093\u3092\u6cbb\u7642\u3059\u308b\u65b9\u6cd5\u5168\u822c\u3092\u6307\u3059<\/strong>\u3053\u3068\u304c\u3042\u308a\u3001\u5927\u304d\u304f\u4e8c\u3064\u306e\u610f\u5473\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u4e00\u3064\u76ee\u306f\u3001<strong>\u79d1\u5b66\u7684\u306b\u6709\u52b9\u6027\u304c\u8a3c\u660e\u3055\u308c\u3066\u304a\u308a\u3001\u8a3a\u7642\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306b\u8a18\u8f09\u3055\u308c\u3001\u6a19\u6e96\u6cbb\u7642\u3068\u306a\u3063\u3066\u3044\u308b<\/strong><strong>\u201c<\/strong><strong>\u514d\u75ab\u7642\u6cd5\u201d<\/strong>\u3067\u3059\u3002<br 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